The Bills are 5-2 against the spread this year. Let’s make it 6-2. Bills, 34-13.

The Bills have a 5-1 record against rookie quarterbacks under Sean McDermott, and they should add another victory in Jacksonville. In Trevor Lawrence, they’ll face their second rookie QB of the season, after wrecking Davis Mills and the Houston Texans, 40-0, in Week 4.

Lawrence, the No. 1 overall pick in the draft, has completed just 59.6% of his passes for 1,703 yards, eight touchdowns and nine interceptions in seven starts. The Jaguars are 1-6, with the lone victory coming on a last-minute field goal against the Miami Dolphins in London.

The Bills are favored by more than two touchdowns. They cover easily. Bills, 38-13.

The Bills needed a lot to get their offense moving last week against the Dolphins, a team that seemingly had nothing to lose against an AFC East foe. The beleaguered Jaguars might have a similar approach, but that won’t be enough to stop a Buffalo offense that didn’t come out of dormancy until the second half, with the two teams tied at 3-3; the Bills scored 23 points in the final 19 minutes.

Speaking of dormant offenses, that term is better suited for the Jaguars, who have scored more than 21 points only once this season: a 23-20 win against the Dolphins in London. Despite 227 passing yards by quarterback Trevor Lawrence, the Jaguars’ offense had no consistency Sunday in a loss at Seattle, and the status of running back James Robinson (heel injury) is in the air for this weekend. Bills, 34-18.