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December 30, 2022
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Healio and Endocrine Today editors have compiled the highest weight problems information from 2022.
Readers have been most within the newest trial knowledge on anti-obesity drugs, corresponding to semaglutide (Wegovy, Novo Nordisk) and tirzepatide (Mounjaro, Eli Lilly), advantages stemming from bariatric surgical procedure, and the proportion of U.S. adults utilizing drugs that will trigger weight acquire.
Here are 10 of Healio’s most-read weight problems tales from 2022.
‘Mind-blowing’ weight reduction with semaglutide extends to adolescents with weight problems
In findings from the STEP Teens part 3a trial offered at ObesityWeek 2022 and printed in The New England Journal of Medicine, once-weekly semaglutide 2.4 mg plus way of life intervention was related to a 16.1% discount in BMI at 68 weeks amongst adolescents with weight problems.
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Weekly tirzepatide confers substantial weight reduction in weight problems with out diabetes: SURMOUNT-1
Data offered on the American Diabetes Association Scientific Sessions revealed practically all adults with weight problems and with out diabetes taking part within the SURMOUNT-1 examine misplaced not less than 5% of their physique weight at 72 weeks with once-weekly tirzepatide, with greater than half of these taking a 15 mg dose shedding not less than 20% of their physique weight.
Surgical weight reduction can decrease obesity-related most cancers, cancer-related mortality
In a examine printed in JAMA, adults with weight problems who deliberately misplaced weight with bariatric surgical procedure have a decrease danger for obesity-related most cancers and cancer-related mortality than those that didn’t have surgical procedure.
20% of adults use drugs that trigger weight acquire
According to knowledge from 2017-2018 National Health and Nutrition Examination Survey, about one in 5 adults within the U.S. stuffed a prescription for a medicine that causes weight acquire. Beta blockers and diabetes drugs have been the commonest obesogenic drugs used.
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Higher physique fats share confers larger mortality danger
A examine printed within the International Journal of Obesity discovered larger ranges of physique fats have been related to a better mortality danger. The affiliation was noticed with a number of physique fats measurements, together with physique fats share, fats mass, fats mass index and visceral adipose tissue.
Personalized eating regimen yields comparable weight reduction as low-fat eating regimen at 6 months
A examine printed in JAMA Network Open discovered a personalised eating regimen doesn’t confer important weight reduction advantages for adults with irregular glucose metabolism and weight problems. Compared with a low-fat eating regimen, a personalised eating regimen concentrating on postprandial glycemic response resulted in the same weight reduction at 6 months.
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US adults, notably these with weight problems, gained weight throughout COVID-19 lockdown
Weight acquire was widespread amongst U.S. adults in the course of the first few months of the COVID-19 pandemic. In a examine printed in Obesity, about 30% of adults reported gaining weight from May 2020 to August 2020, with 18.4% having a weight acquire of not less than 2 kg.
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New hormone-based therapies poised to develop weight problems therapy choices
A presenter at ObesityWeek 2022 highlighted plenty of hormone-based therapies that could possibly be useful for adults with weight problems. Multiple new brokers which might be presently in growth may significantly develop the variety of anti-obesity drugs accessible within the close to future.
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Weight loss reduces hedonic starvation, bariatric surgical procedure lowers meals cravings
In a examine printed in Obesity, researchers discovered that weight reduction was related to lowered hedonic starvation, impartial of modality, and bariatric surgical procedure was linked to useful modifications in meals reward and preferences.
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