The Dallas Cowboys and Philadelphia Eagles meet in an early-season showdown for supremacy in the NFC East on Sunday Night Football. The Eagles (5-0) are off to their best start in 18 years as they look to dethrone the defending NFC East champions. The Cowboys (4-1), who won the division with a 12-5 mark in 2021, have won four consecutive games following an opening-night loss to the Tampa Bay Buccaneers. Dallas has defeated Philadelphia the last three times they have met.

Kickoff from Lincoln Financial Field in Philadelphia is set for 8:20 p.m. ET. Philadelphia is a 6.5-point favorite in the latest Cowboys vs. Eagles odds from Caesars Sportsbook, while the over/under for total points scored is 42.5. Before making any Eagles vs. Cowboys picks, you need to see the NFL predictions and betting advice from SportsLine’s advanced computer model.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 6 of the 2022 NFL season on an incredible 146-106 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Cowboys vs. Eagles and just locked in its picks and Sunday Night Football predictions. You can head to SportsLine now to see the model’s picks. Here are several NFL odds and betting lines for Eagles vs. Cowboys:

• Cowboys vs. Eagles spread: Eagles -6.5
• Cowboys vs. Eagles over-under: 42.5 points
• Cowboys vs. Eagles money line: Cowboys +228, Eagles -285
• DAL: Cowboys are 6-0 against the spread in their last six October games
• PHI: Eagles are 4-1-1 ATS in their last six home games
• Cowboys vs. Eagles picks: See picks at SportsLine

Featured Game | Philadelphia Eagles vs. Dallas Cowboys

Why the Eagles can cover

Quarterback Jalen Hurts had 300 yards, including 239 passing, with two rushing TDs in the Week 5 win at Arizona. Hurts has seven career games with two or more rushing touchdowns, tied for the second-most by a quarterback all-time. He has 19 rushing TDs in 24 starts, also the most by a quarterback in his first 25 career starts. Hurts has also been dangerous when playing at home. He has 12 touchdowns, including eight rushing, in his past five home starts.

Philadelphia’s defense is stout. Among its leaders is defensive end Brandon Graham. Graham had one sack, one forced fumble and one fumble recovery in the last home meeting with the Cowboys and looks for his third game in a row against Dallas with a sack. For the season, he has 14 tackles, including seven solo, with three sacks, three tackles for loss, one pass breakup and one forced fumble.

Why the Cowboys can cover

Wide receiver CeeDee Lamb leads the team with 28 receptions for 341 yards (12.2 average) and two touchdowns. He has four explosive plays of 20 yards or more and 130 yards after the catch. Lamb will look for his fifth game in a row with five or more catches and 50 or more receiving yards. His best game so far this year was an eight-catch, 87-yard and one TD performance against the New York Giants in Week 3.

Defensively, linebacker Micah Parsons has been a disruptive playmaker. Parsons had two sacks and a forced fumble in a Week 5 win over the Los Angeles Rams, and is one of three players (Nick Bosa and T.J. Watt) with six games of two or more sacks since 2021. Parsons has three sacks and seven tackles for loss in three career Sunday Night Football games. He will be looking for his third game in a row on SNF with a sack and his fourth game in a row with a tackle for loss.

How to make Cowboys vs. Eagles picks on SNF

SportsLine’s model is leaning Over on the point total, with the model calling for 44 combined points. The model also says one side of the spread has all the value. You can only see the model’s SNF picks at SportsLine.

So who wins Eagles vs. Cowboys on Sunday Night Football? And which side of the spread has all the value? Visit SportsLine now to see which side of the Eagles vs. Cowboys spread you need to jump on, all from the model on a 146-106 roll on NFL picks, and find out.