After Miami’s Sixto Sanchez got through the first four innings on 43 pitches, Gurriel snapped the rookie right-hander’s 11-inning scoreless string with a two-run shot for a 2-0 lead in the fifth. Gurriel drove Sanchez’s 0-1 slider over the left-center wall for his fifth homer.

Ryu (3-1) allowed one run and six hits, walked two and matched a season high with eight strikeouts.

A.J. Cole and Rafael Dolis each pitched scoreless innings and Anthony Bass got his fourth save for the Blue Jays, who are 12-12 in one-run games.

Jonathan Villar had two hits in his second game since joining the Blue Jays in a trade with Miami on Monday.

Sanchez (1-1) was lifted after seven innings. He allowed six hits and struck out five.

Miami scored its run on Garrett Cooper’s RBI single in the fifth.

The Blue Jays committed three baserunning blunders that ended innings. Jonathan Villar was thrown out attempting to stretch a single into a double in the first, and Miami catcher Jorge Alfaro picked off Gurriel at first in the second and Villar at third in the fourth.