Portland police made multiple arrests on Friday as the Oregon city nears 100 days of demonstrations against widespread racism and police brutality in the United States.

Portland has become the epicenter of demonstrations, with protests taking place nightly over the last three months calling for policing and social justice reforms. These protests have sometimes turned violent.

Police arrested 27 people, mostly on charges of interfering with law enforcement or disorderly conduct after not complying with orders to clear the area where they assembled and throwing items at officers.

“Officers began to make targetted arrests and in some cases moved the crowd back and kept them out of the street,” according to a press released issued on Saturday.

Demonstrations against racism and police brutality have swept the United States since the death in May of George Floyd, a 46-year-old Black man who died after a Minneapolis police officer knelt on his neck for nearly nine minutes.

In Rochester, New York on Friday night nearly 1,000 demonstrators marched downtown to protest the March death of black man Daniel Prude in police custody. Police used pepper balls to clear protesters during protests the night before, according to local news reports.

Police shot and killed a self-declared anti-fascist activist in Washington state on Thursday night as they moved in to arrest him on suspicion he fatally shot a right-wing counterprotester last weekend in Portland.

The Trump administration deployed federal forces to Portland in July to crack down on the protests. Trump signed a memo on Wednesday that threatens to cut federal funding to “lawless” cities, including Portland.

His Democratic challenger in the Nov. 3 presidential election, Joe Biden, has accused Trump of stoking violence with his rhetoric.