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Study exhibits our intestine microbes could decide bone well being

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Study exhibits our intestine microbes could decide bone well being

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This is important as a result of low bone density will increase the chance of growing osteoporosis, affecting thousands and thousands of individuals worldwide over the age of fifty, and might enhance the chance of fractures.

Published Date – 04:40 PM, Sun – 24 September 23


Study shows our gut microbes may determine bone health



New York: Our intestine microbiome could have a job to play in our bone health and keep off the chance of osteoporosis and fractures, suggests a examine.

The findings, revealed in Frontiers in Endocrinology, may someday present the chance to change intestine microbiomes to attain higher bone well being, as scientists be taught extra about “osteomicrobiology” — a brand new time period just lately used to characterise this relationship.

A staff from Hebrew SeniorLife and Hinda and Arthur Marcus Institute for Aging Research within the US carried out the examine of older males to find out whether or not they may discover a doubtlessly modifiable issue contributing to skeletal well being.

They used high-resolution imaging of the arm and leg.

This is important as a result of low bone density will increase the chance of growing osteoporosis, affecting thousands and thousands of individuals worldwide over the age of fifty, and might enhance the chance of fractures.

The staff discovered that micro organism known as Akkermansia, which has been related to weight problems, and Clostridiales bacterium DTU089, had unfavourable associations with bone well being for older adults.

DTU089, a bacterium from the category Clostridia, has been described to be extra ample in folks with decrease bodily exercise, and decrease protein consumption.

It might be important as a result of prior research have discovered protein consumption and bodily exercise have a particular connection to skeletal well being.

“We found patterns in which greater abundance of microbiota were associated with worse measures of bone density and microarchitecture. In fact, some bacteria were associated with differences in the bone cross sectional area, suggesting the possibility that certain microbes could influence how the bone changes size with ageing,” stated Douglas P. Kiel, Senior Scientist on the Marcus Institute.

“It is premature to know if the bacterial organisms themselves may have effects on skeletal health,” he added.

The staff proposed extra research to realize insights concerning associations between particular bacterial species within the gut and skeletal integrity.

They additionally hope to determine particular useful pathways influenced by the micro organism that would affect the skeleton.”

“For example, some bacteria can lead to low levels of inflammation that may affect bone health. Ultimately, if findings like this are confirmed, we may be able to target the gut microbiome to influence skeletal health,” Kiel stated.

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