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The test should be conducted onsite under strict medical supervision. (Representational)
New Delhi:
Indian Council of Medical Research (ICMR) has recommended the use of Standard Q COVID-19 Ag detection assay (antigen detection test) as a point of care diagnostic assay for testing under certain settings in combination with RT-PCR test.
Those who test negative for COVID-19 by rapid antigen test should be definitely tested sequentially by RT-PCR to rule out infection, whereas a positive test should be considered as a true positive and does not need reconfirmation by RT-PCR test, said ICMR in an advisory on Sunday.
One of the brief descriptions of the Standard Q COVID-19 Ag detection is that the test can be interpreted as positive or negative after 15 minutes of putting the sample into the well by appearance of test and control lines, which can be read with a naked eye, requiring no specialized equipment. Maximum duration for interpreting a positive or negative test is 30 minutes. After that the test strip should be discarded. The test kit should be stored between 2deg to 30deg C.
In view of its high specificity while relatively low sensitivity, ICMR recommends the use of Standard Q COVID-19 Ag detection assay as a point of care diagnostic assay for testing in the following settings in combination with the gold standard RT-PCR test–
A. Containment zones or hotspots (to be performed onsite under strict medical supervision and maintaining kit temperature between 2deg to 30deg C.):
i) All symptomatic Influenza Like Illness (ILI). ii) Asymptomatic direct and high-risk contacts with co-morbidities (lung disease, heart disease, liver disease, kidney disease, diabetes, neurological disorders, blood disorders) of a confirmed case to be tested once between day 5 and day 10 of coming into contact.
B. Healthcare settings (to be performed onsite under strict medical supervision and maintaining kit temperature between 2deg to 30deg C):
i) All symptomatic ILI patients presenting in a healthcare setting and are suspected of having COVID-19 infection. ii) Asymptomatic patients who are hospitalized or seeking hospitalization, in the following highrisk groups: Patients undergoing chemotherapy, Immunosuppressed patients including those who are HIV+; Patients diagnosed with malignant disease; Transplant patients; Elderly patients (>65 yrs of age) with co-morbidities (lung disease, heart disease, liver disease, kidney disease, diabetes, neurological disorders, blood disorders)
iii) Asymptomatic patients undergoing aerosol-generating surgical / non-surgical interventions: Elective/emergency surgical procedures like neurosurgery, ENT surgery, dental procedures; Non-surgical interventions like bronchoscopy, upper GI endoscopy and dialysis;
ILI case is defined as one with acute respiratory infection with fever >= 38 degree Celsius and cough.
Use of the rapid antigen test is recommended in A & B categories above subject to the following conditions: i) Suspected individuals who test negative for COVID-19 by rapid antigen test should be definitely tested sequentially by RT-PCR to rule out infection, whereas a positive test should be considered as a true positive and does not need reconfirmation by RT-PCR test.
ii) Samples (only nasopharyngeal swabs) to be collected by a trained healthcare worker following full infection control practices including use of proper PPE.
iii) The test should be conducted onsite under strict medical supervision and within one hour of sample collection in extraction buffer.
Giving a background, the ICMR said, “Real time RT-PCR is the gold standard frontline test for diagnosis of COVID19. Various open and closed RT-PCR platforms (Open systems RT-PCR machines, TrueNat and CBNAAT) are currently being used for COVID19 diagnosis in India.”
“All these platforms require specialized laboratory facilities in terms of equipment, biosafety and biosecurity. Minimum time taken for the test varies between different systems with a minimum of 2-5 hours including the time taken for sample transportation. These specifications limit the widespread use of the RT-PCR test and also impedes quick augmentation of testing capacity in various containment zones and hospital settings.”
“In view of this, there is urgent need of a reliable point-of-care rapid antigen detection test with good sensitivity and specificity for early detection of the disease,” it said.
There are no reliable antigen detection tests available worldwide, which could be used as rapid point of care tests for quick detection of COVID-19 positive patients. Such tests would help in proper implementation of the Government strategy to test, track and treat. Such tests will also help in allaying the anxiety and fear of healthcare workers and aid in better clinical management of the patients.
In view of this, an independent two site evaluation of the only available or standalone antigen detection assay: Standard Q COVID-19 Ag detection kit, was conducted with an aim to evaluate its sensitivity, specificity and feasibility of use as a point-of-care test for early detection of SARS-CoV-2.
World
77,78,881Cases
36,42,481Active
37,06,353Recovered
4,30,047Deaths
Coronavirus has spread to 188 countries. The total confirmed cases worldwide are 77,78,881 and 4,30,047 have died; 36,42,481 are active cases and 37,06,353 have recovered as on June 14, 2020 at 9:18 am.
India
3,20,922 11929Cases
1,49,348 3569Active
1,62,379 8049Recovered
9,195 311Deaths
In India, there are 3,20,922 confirmed cases including 9,195 deaths. The number of active cases is 1,49,348 and 1,62,379 have recovered as on June 14, 2020 at 8:00 am.
State & District Details
| State | Cases | Active | Recovered | Deaths |
|---|---|---|---|---|
|
DistrictCases Akola757 Aurangabad1974 Dhule228 Jalgaon1039 Mumbai45478 Mumbai Suburban5363 Nagpur692 Nashik1575 Palghar1421 Pune9920 Satara629 Solapur1291 Thane13660 Yavatmal150 Ahmednagar190 Amravati291 Beed54 Bhandara41 Buldhana88 Chandrapur32 Hingoli208 Jalna201 Kolhapur646 Latur139 Nanded176 Nandurbar42 Parbhani78 Raigad1462 Ratnagiri350 Sangli145 Gadchiroli42 gondia69 Osmanabad125 Sindhudurg114 Wardha11 Washim13 |
104568 3427 |
51392 1764 |
49346 1550 |
3830 113 |
|
DistrictCases Chittoor319 Guntur511 Krishna557 Kurnool795 Sri Potti Sriramulu Nell*296 Anantapur428 East Godavari356 Prakasam104 Srikakulam183 Visakhapatnam103 West Godavari199 Y.S.R.205 Vizianagaram23 |
5965 285 |
2688 193 |
3195 90 |
82 2 |
|
DistrictCases Bengaluru Rural40 Bengaluru Urban529 Mysuru107 Bagalkote103 Ballari60 Belagavi337 Bidar219 Chikkaballapura149 Dakshina Kannada179 Dharwad61 Gadag45 Kalaburagi669 Mandya346 Tumakuru36 Uttara Kannada95 Vijayapura201 Chamarajanagara0 Chikkamagaluru19 Chitradurga14 Davangere204 Hassan205 Haveri24 Kodagu4 Kolar29 Koppal5 Raichur369 Ramanagara3 Shivamogga67 Udupi1176 Yadgir538 |
6824 308 |
3095 98 |
3648 208 |
81 2 |
|
DistrictCases North Goa57 South Goa69 |
523 60 |
453 59 |
70 1 |
0 |
|
DistrictCases Chengalpattu1314 Chennai23324 Kanchipuram503 Madurai322 Namakkal83 Ranipet133 Thanjavur130 Thiruvallur774 Thiruvarur67 Tiruppur116 Vellore71 Virudhunagar185 Ariyalur444 Coimbatore188 Cuddalore477 Dharmapuri15 Dindigul175 Erode75 Kallakurichi324 Kanniyakumari110 Karur88 Nagapattinam99 Perambalur133 Pudukkottai53 Ramanathapuram119 Salem258 Sivaganga46 Tenkasi103 The Nilgiris17 Theni129 Tiruchirappalli119 Tirunelveli433 Tirupathur45 Tiruvannamalai496 Tuticorin333 Villupuram509 Krishnagiri43 |
42687 1989 |
18881 597 |
23409 1362 |
397 30 |
|
DistrictCases Kannur357 Kottayam73 Alappuzha76 Idukki40 Kasaragod333 Kollam118 Kozhikode90 Malappuram119 Palakkad224 Pathanamthitta98 Thiruvananthapuram104 Thrissur106 Ernakulam60 Wayanad36 |
2407 85 |
1342 39 |
1046 46 |
19 |
|
DistrictCases Raipur46 Korba100 Balod41 Baloda Bazar85 Balrampur17 Bastar2 Bemetara21 Bijapur2 Bilaspur100 Dantewada0 Dhamtari6 Durg31 Gariyaband10 Janjgir-Champa56 Jashpur77 Kabirdham52 Kanker19 Kondagaon0 Korea39 Mahasamund54 Mungeli87 Narayanpur0 Raigarh47 Rajnandgaon52 Sukma0 Surajpur9 Surguja14 |
1512 83 |
875 2 |
631 81 |
6 |
|
DistrictCases Hyderabad2475 MedchalMalkajgiri75 Ranga Reddy183 Suryapet87 Vikarabad40 Warangal Urban32 Adilabad22 Jagitial77 Jangoan8 Jayashankar Bhupalapally9 Jogulamba Gadwal40 Kamareddy11 Karimnagar17 Khammam26 Kumuram Bheem Asifabad8 Mahabubnagar30 Mancherial43 Medak11 Nalgonda33 Narayanpet3 Nirmal21 Nizamabad76 RajannaSircilla16 Sangareddy26 Bhadradri Kothagudem5 Mahabubabad10 Mulugu3 Nagarkurnool8 Peddapalli5 Siddipet7 Wanaparthy1 Warangal Rural4 YadadriBhuvanagiri40 |
4737 253 |
2203 171 |
2352 74 |
182 8 |
|
DistrictCases Baleshwar190 Bhadrak137 Jajapur322 Dhenkanal36 Kalahandi33 Kendrapara164 Khordha238 Koraput16 Sundargarh102 Anugul26 Balangir129 Bargarh16 Boudh34 Cuttack155 Deogarh33 Gajapati61 Ganjam581 Jagatsinghapur91 Jharsuguda8 Kandhamal28 Kendujhar34 Malkangiri20 Mayurbhanj73 Nabarangpur2 Nayagarh86 Nuapada69 Puri103 Rayagada2 Sambalpur16 Sonepur29 |
3723 225 |
1119 105 |
2594 120 |
10 |
|
DistrictCases Barwani60 Bhopal1880 Dewas140 Dhar132 East Nimar266 Gwalior211 Indore3839 Jabalpur276 Ujjain799 Agar Malwa15 Alirajpur3 Betul35 Burhanpur351 Chhindwara16 Dindori29 Harda4 Hoshangabad37 Khargone196 Mandsaur112 Morena109 Raisen71 Ratlam51 Sagar228 Shajapur39 Shandol14 Sheopur26 Tikamgarh18 Vidisha37 Anuppur22 Ashoknagar13 Balaghat9 Bhind87 Chhatarpur35 Damoh26 Datia12 Guna8 Jhabua14 Katni3 Mandla15 Narsinghpur17 Neemuch319 Niwari0 Panna20 Rajgarh31 Rewa39 Satna24 Sehore12 Seoni2 Shivpuri15 Sidhi17 Singrauli13 Umaria10 |
10641 198 |
2817 15 |
7377 176 |
447 7 |
|
DistrictCases Ahmadabad17125 Anand107 Arvalli134 Banas Kantha147 Bhavnagar146 Gandhinagar410 PanchMahals107 Surat2311 Vadodara1555 Bharuch56 Botad55 Chhotaudepur37 Dang5 Dohad43 GirSomnath45 Jamnagar63 Kachchh99 Kheda98 Mahesana159 Mahisagar125 Narmada25 Naysari35 Patan105 Rajkot135 SabarKantha101 Surendranagar55 Tapi6 Valsad47 Amreli16 DevbhumiDwarka22 Junagadh31 Morbi4 Porbandar11 |
23038 511 |
5707 88 |
15883 390 |
1448 33 |
|
DistrictCases Ajmer379 Banswara91 Bharatpur563 Jaipur2177 Jhalawar329 Jodhpur1748 Kota503 Nagaur500 Alwar90 Barmer34 Bhilwara250 Bikaner112 Chittorgarh188 Churu81 Dausa61 Dholpur60 Dungarpur374 Hanumangarh31 Jaisalmer53 Jhunjhunu64 Karauli17 Pali352 Rajsamand140 SawaiMadhopur26 Sikar231 Tonk171 Udaipur724 Baran59 Bundi5 Ganganagar8 Jalore164 Pratapgarh14 Sirohi130 |
12401 333 |
2782 |
9337 439 |
282 10 |
|
DistrictCases Faridabad867 Sonipat404 Ambala93 Bhiwani60 CharkiDadri43 Fatehabad38 Gurugram2950 Hisar98 Jhajjar114 Jind38 Kaithal48 Karnal104 Kurukshetra55 Nuh68 Palwal120 Panchkula39 Panipat78 Rohtak145 Sirsa50 Yamunanagar19 Mahendragarh47 Rewari56 |
6749 415 |
3868 79 |
2803 328 |
78 8 |
|
DistrictCases Agra933 Aligarh215 Amroha80 Bareilly17 Bijnor157 Bulandshahr166 Firozabad190 Gautam Buddha Nagar1119 Kanpur Nagar286 Lucknow386 Mathura129 Meerut504 Moradabad252 Muzaffarnagar117 Rae Bareli78 Rampur203 Saharanpur298 Sant Kabeer Nagar132 Varanasi243 Auraiya37 Ayodhya120 Azamgarh138 Baghpat68 Bahraich73 Balrampur49 Banda27 Basti214 Bhadohi60 Budaun23 Etah52 Etawah46 Ghaziabad794 Ghazipur159 Gonda59 Gorakhpur166 Hapur225 Hardoi49 Jalaun41 Jaunpur194 Jhansi41 Kannauj69 Kasganj16 Kaushambi6 Mainpuri46 Mau48 Mirzapur22 Pilibhit15 Pratapgarh15 Prayagraj30 Sambhal116 Shamli40 Shravasti23 Sitapur32 Sultanpur97 Unnao42 Ambedkar Nagar92 Amethi206 Ballia60 Barabanki168 Chandauli38 Chitrakoot4 Deoria143 Farrukhabad36 Fatehpur3 Hamirpur3 Hathras43 Kanpur Dehat4 Kheri72 Kushi Nagar67 Lalitpur3 Maharajganj85 Mahoba3 Shahjahanpur25 Siddharth Nagar159 Sonbhadra10 |
13118 502 |
4858 216 |
7875 266 |
385 20 |
|
DistrictCases Central4817 East2472 New Delhi3405 North3059 North East1914 North West5463 Shahdara1580 South2329 South East2446 South West2391 West4768 |
38958 2134 |
22742 530 |
14945 1547 |
1271 57 |
|
DistrictCases Dhubri30 Goalpara19 Marigaon50 Baksa14 Barpeta28 Biswanath16 Bongaigaon12 Cachar80 Charaideo29 Chirang6 Darrang20 Dhemaji47 Dibrugarh61 Dima Hasao86 Golaghat203 Hailakandi57 Hojai89 Jorhat24 Kamrup42 Kamrup Metro276 KarbiAnglong13 Karimganj85 Kokrajhar37 Lakhimpur57 Majuli2 Nagaon143 Nalbari23 Sivasagar20 Sonitpur27 South SalmaraMancachar4 Tinsukia84 Udalguri28 West KarbiAnglong5 |
3718 220 |
2126 173 |
1584 47 |
8 |
|
DistrictCases East District3 North District0 South District3 West District0 |
63 |
59 |
4 2 |
0 |
|
DistrictCases Buxar134 Gaya115 Munger188 Patna279 Rohtas256 Arwal52 Aurangabad75 Banka134 Begusarai243 Bhagalpur266 Bhojpur103 Darbhanga143 Gopalganj123 Jehanabad178 Kaimur (bhabua)105 Lakhisarai72 Madhepura82 Madhubani199 Nalanda123 Nawada122 PurbiChamparan138 Purnia135 Saran101 Siwan139 Vaishali87 Araria68 Jamui47 Katihar175 Khagaria253 Kishanganj75 Muzaffarpur96 Pashchim Champaran57 Saharsa88 Samastipur139 Sheikhpura118 Sheohar20 Sitamarhi73 Supaul87 |
6290 187 |
2295 |
3956 369 |
39 3 |
|
DistrictCases 24 Paraganas North1031 24 Paraganas South281 Darjeeling97 Howrah1435 Jalpaiguri88 Kalimpong18 Kolkata2777 Maldah235 Medinipur East153 Medinipur West159 Hooghly604 Murshidabad125 Nadia139 Paschim Bardhaman70 Purba Bardhaman130 Alipurduar39 Bankura116 Birbhum206 Coochbehar210 Dinajpur Dakshin50 Dinajpur Uttar216 Jhargram9 Purulia66 |
10698 454 |
5693 106 |
4542 336 |
463 12 |
|
DistrictCases South Andamans33 Nicobars1 North And Middle Andaman1 |
38 |
5 |
33 |
0 |
|
DistrictCases Pondicherry111 Karaikal2 Mahe4 Yanam0 |
176 19 |
92 4 |
82 15 |
2 |
|
DistrictCases Anjaw0 Changlang31 Dibang Valley0 East Kameng0 East Siang1 Kamle0 KraDaadi0 KurungKumey0 Leparada0 Lohit3 Longding0 Lower Dibang Valley0 Lower Siang0 Lower Subansiri0 Namsai2 PakkeKessang1 Papum Pare8 Shi Yomi0 Siang0 Tawang1 Tirap0 Upper Siang1 Upper Subansiri0 West Kameng0 West Siang1 |
87 20 |
83 20 |
4 |
0 |
|
DistrictCases Dimapur20 Kiphire3 Kohima7 Longleng0 Mokokchung0 Mon8 Peren2 Phek1 Tuensang3 Wokha0 Zunheboto0 |
163 7 |
87 |
76 27 |
0 |
|
DistrictCases Dadra And Nagar Haveli20 |
0 |
0 |
0 |
0 |
|
DistrictCases Ranchi148 Bokaro16 Deoghar5 Dhanbad32 Garhwa80 Giridih19 Hazaribagh110 Jamtara2 Koderma58 Simdega48 Chatra1 Dumka5 East Singhbum170 Godda2 Gumla28 Khunti10 Latehar14 Lohardaga8 Pakur4 Palamu27 Ramgarh75 Sahebganj0 SaraikelaKharsawan20 West Singhbhum21 |
1711 94 |
887 |
816 144 |
8 |
|
DistrictCases Gomati74 North Tripura14 Dhalai196 Khowai24 Sepahijala174 South Tripura53 Unakoti49 West Tripura45 |
1046 85 |
730 48 |
315 37 |
1 |
|
DistrictCases Kargil77 LehLadakh43 |
437 198 |
368 192 |
68 6 |
1 |
|
DistrictCases Anantnag395 Bandipora175 Shopian255 Srinagar300 Baramulla271 Budgam110 Ganderbal37 Jammu138 Kathua53 Kulgam295 Kupwara231 Rajouri39 Ramban151 Reasi26 Samba25 Udhampur155 Mirpur0 Muzaffarabad0 Doda27 Kishtwar10 Poonch35 Pulwama108 |
4878 148 |
2554 |
2269 183 |
55 2 |
|
DistrictCases Chamba29 Hamirpur117 Kangra105 Sirmaur11 Solan32 Una41 Bilaspur21 Kinnaur2 Kullu4 Lahaul And Spiti0 Mandi21 Shimla10 |
502 16 |
183 |
313 16 |
6 |
|
DistrictCases Jalandhar297 Ludhiana293 Patiala132 Amritsar485 Barnala25 Faridkot74 Firozepur50 Gurdaspur154 Hoshiarpur140 Kapurthala44 Mansa31 Moga65 Pathankot86 S.A.S Nagar137 Sangrur107 Shahid Bhagat Singh Nagar (Nawanshahr)99 Sri Muktsar Sahib71 Tarn Taran163 Bathinda60 Fatehgarh Sahib57 Fazilka53 Rupnagar (Ropar)74 |
3063 77 |
671 30 |
2327 45 |
65 2 |
|
DistrictCases Haridwar94 Dehradun370 Nainital323 Almora71 Bageshwar31 Chamoli36 Champawat45 PauriGarhwal36 Pithoragarh43 Rudraprayag30 Tehri Garhwal110 Udam Singh Nagar83 Uttar Kashi24 |
1785 61 |
685 |
1077 130 |
23 2 |
|
DistrictCases Bishnupur7 Chandel5 Churachandpur32 Imphal East10 Imphal West21 Jiribam3 Kakching2 Kamjong5 Kangpokpi26 Noney1 Pherzawl3 Senapati6 Tamenglong2 Tengnoupal9 Thoubal18 Ukhrul4 |
449 64 |
358 50 |
91 14 |
0 |
|
DistrictCases Chandigarh313 |
345 11 |
54 11 |
286 |
5 |
|
DistrictCases East Khasi Hills22 East Garo Hills0 East Jaintia Hills0 North Garo Hills1 Ribhoi0 South Garo Hills0 South West Garo Hills4 South West Khasi Hills0 West Garo Hills5 West Jaintia Hills1 West Khasi Hills1 |
44 |
21 |
22 |
1 |
|
DistrictCases Aizawl10 Champhai0 Hnahthial0 Khawzawl0 Kolasib11 Lawngtlai2 Lunglei2 Mamit8 Saiha0 Saitual1 Serchhip0 |
107 3 |
106 3 |
1 |
0 |
|
DistrictCases Lakshadweep District0 |
0 |
0 |
0 |
0 |
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