“I feel like the whole game my fastball was, by far, my best pitch tonight,” Sheffield said. “I was able to locate inside and that was the plan, to jam them.”

Marmolejos hit a two-run homer in the fifth to push the Mariners lead to 7-2. It was the rookie’s fifth homer of the season. France is hitting .379 (11-of-29) since coming to the Mariners in a mid-season trade from the Padres.

“Getting consistent at-bats, getting settled at the plate, it’s made a huge difference,” France said. “To come in and contribute right away feels good.”

Gallen (1-2) set a big-league record last week after giving up three runs or less in the first 23 starts of his career. That streak was broken on Monday when he gave up four runs over five innings against the San Francisco Giants.

The right-hander had more trouble against the Mariners, giving up seven runs on seven hits, including two doubles and two homers. He walked five and struck out six, needing 98 pitches to get through five innings.

“This one was a little uncharacteristic,” Arizona manager Torey Lovullo said of Gallen’s outing. “He had a few misfires early and had trouble getting started. I think he’s going to get back on the right track.”

The Diamondbacks became the first team in the National League with 30 losses, falling to 17-30 for the season.